Bruno's are muscle bound members of society. They can be created multiple ways to be made into a Bruno with each method having its own drawbacks. They do not have a reputation for living long.
Some people with the right appearance are called a "natural Bruno", because they fit the paradigm.
↑I tried to avoid staring as we passed a collection of six men with roughly identical builds, each with slabs of muscle, hunched-over posture, and arms as thick around as their legs, which were thicker around than I was. Where the next guy could pick up a given maximum weight, these Brunos could carry two of those ‘next guys’ and the weights besides.
I knew the type – manual laborers, taking some cheap and freely available option to alter themselves. - Excerpt from Bleeding Edge 8.3
↑He was a ‘Bruno’. While Bruno was slang for a brute, a guy that was more strong than smart, it also was the term used most often to describe the men and the exceedingly rare women who went to back alley clinics and walked out with more muscle than they’d had when they started. Sometimes it was drugs, sometimes it was a rewriting of their physical makeup, and sometimes it was grafts, from vat-grown sources or from animals.
Most did it because the cost of the procedure was low, compared to the added dollars they could make being manual laborers. It meant a year or two to pay off the medical expenses, then a few decades of living like a king. Relatively speaking, anyway, in a place like Lugh.
But the drugs meant dependency and tolerance. The rewriting of one’s makeup always had other consequences in the long run. Grafts from animals meant possible rejection or having to take drugs, and grafts from vat-grown life didn’t always last that long, meaning more surgeries and replacements.
↑So you say, but do you know how many years those muscles you bought are going to take from you? There are no old Brunos. [...] “An excellent doctor won’t run into that problem,” Jamie said. Before I could make a counter argument, he provided it himself, “But he said it wasn’t top dollar work.” - Excerpt from Bleeding Edge 8.4